PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701

General Details:

Name:: PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701
Steward:: PhenX
Definition:: A biospecimen is collected from the respondent to measure cotinine, a marker of either smoking or of environmental tobacco smoke exposure. One of the most common methods is via a urine sample obtained from the respondent. Cotinine in urine is measured by gas chromatography mass spectrometry (GC-MS). Other biological matrices (blood, hair, saliva) may be used to measure cotinine. Information about collection and analysis of those matrices is found in the Supplemental Information: Blood, Hair, and Saliva Assays for Tobacco Smoke Exposure. Caffeine may interfere with the accuracy of the results. During the gas chromatography analysis, this interference can be minimized by ramping up the temperature and eluting the caffeine later than the cotinine.
Registration Status:: Qualified

Designation:: PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701
Tags:: Long Common Name

Definition:: A biospecimen is collected from the respondent to measure cotinine, a marker of either smoking or of environmental tobacco smoke exposure. One of the most common methods is via a urine sample obtained from the respondent. Cotinine in urine is measured by gas chromatography mass spectrometry (GC-MS). Other biological matrices (blood, hair, saliva) may be used to measure cotinine. Information about collection and analysis of those matrices is found in the Supplemental Information: Blood, Hair, and Saliva Assays for Tobacco Smoke Exposure. Caffeine may interfere with the accuracy of the results. During the gas chromatography analysis, this interference can be minimized by ramping up the temperature and eluting the caffeine later than the cotinine.
Tags:: Source: Regenstrief LOINC

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Language Code:: en-US
Document:: Man, C. N., L.-H. Gam, Ismail, S., Lajis, R., Awang, R. 2006. Simple, rapid and sensitive assay method for simultaneous quantification of urinary nicotine and cotinine using gas chromatography-mass spectrometry. J of Chromatography B 844(2): 322-327.

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Language Code:: en-US
Document:: Bernowitz, N.L. (1999). Biomarkers of Environmental Tobacco Smoke Exposure. Environ Health Perspect. 107(Suppl 2):3 49-355.

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Language Code:: en-US
Document:: Kuo, H.W., Yang, J.S., Chiu, M.C. (2002). Determination of urinary and salivary cotinine using gas and liquid chromatography and enzyme-linked immunosorbent assay. J Chromatogr B Analyt Technol Biomed Life Sci. 768(2):297-303.

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Language Code:: en-US
Document:: Dhar, Preeti. (2004). Measuring tobacco smoke exposure: quantifying nicotine/cotinine concentration in biological samples by colorimetry, chromatography and immunoassay methods. J Pharm Biomed Anal, 35(2004), 155-168.

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Language Code:: en-US
Document:: Benowitz, Neal L. (1996). Cotinine as a biomarker of environmental tobacco smoke exposure. Epidemiol Rev, 18(2), 188-204.

Key:

Related Names

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Exp	Pan	Panel
PANEL.PHENX	Panl	Pnl
Point in time	Random	Resp urine assay smoke exp proto
Tob smoke exposure

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Related Codes

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Code System	Code	Code Text	Code Version
https://www.phenxtoolkit.org	91701	biomarker_of_exposure_to_nicotine_containing_products___urine

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Fully-Specified Name

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Component	Property	Time	System	Scale	Method
PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701	-	Pt	^Patient	-	PhenX

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Basic Attributes

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Class	Type	First Released	Last Updated	Change Reason	Panel Type
PANEL.PHENX	Clinical	Version 2.36	Version 2.66	Updated the PhenX ID from "PhenX." to "PX" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.	Panel