Fasting C-peptide proto

General Details:

Name:: Fasting C-peptide proto
Steward:: PhenX
Definition:: This protocol provides instructions for drawing, processing and storing blood according to the National Health and Nutrition Examination Survey (NHANES) methods. As there are no standard assays for C-peptide, the protocol also provides basic guidelines to aid comparability among different studies. Although all three are valuable stand alone measures and all should be collected if resources are available, the Diabetes Working Group recommends that investigators prioritize Insulin 1st, C-peptide 2nd and Proinsulin 3rd. This is because results from the Insulin bioassay can be combined with results from Fasting Plasma Glucose bioassay to derive the homeostatic model assessment (HOMA) of insulin resistance and pancreatic beta cell function. The Diabetes Working Group notes that while it is not the preferred method, the C-peptide Assay can be performed on individuals who have not met the fasting requirements.
Registration Status:: Qualified

Designation:: PhenX - fasting C-peptide assay for residual beta cell function protocol 141201
Tags:: Long Common Name

Definition:: This protocol provides instructions for drawing, processing and storing blood according to the National Health and Nutrition Examination Survey (NHANES) methods. As there are no standard assays for C-peptide, the protocol also provides basic guidelines to aid comparability among different studies. Although all three are valuable stand alone measures and all should be collected if resources are available, the Diabetes Working Group recommends that investigators prioritize Insulin 1st, C-peptide 2nd and Proinsulin 3rd. This is because results from the Insulin bioassay can be combined with results from Fasting Plasma Glucose bioassay to derive the homeostatic model assessment (HOMA) of insulin resistance and pancreatic beta cell function. The Diabetes Working Group notes that while it is not the preferred method, the C-peptide Assay can be performed on individuals who have not met the fasting requirements.
Tags:: Source: Regenstrief LOINC

ID:
Title:
URI:
Provider Org:
Language Code:: en-US
Document:: American Diabetes Association. (2010). Diagnosis and classification of diabetes mellitus. Diabetes Care, 33 (Supplement 1), S11 - S61.

ID:
Title:
URI:
Provider Org:
Language Code:: en-US
Document:: Centers for Disease Control and Prevention (CDC). National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey Questionnaire. Laboratory Procedures Manual. Hyattsville, MD: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 2007.

ID:
Title:
URI:
Provider Org:
Language Code:: en-US
Document:: Marques, RG, Fontaine, MJ, & Rogers, J. (2004). C-peptide - much more than a byproduct of insulin biosynthesis. Pancreas, 29(3), 231-238.

Key:

Related Names

Value:

B	C peptide	Connecting peptide of insulin
Fasting C-peptide proto	FCN	Func
Funct	Pan	Panel
PANEL.PHENX	Panl	Pept
Pnl	Point in time	Pro-insulin c peptide
Random

Key:

Related Codes

Value:

Code System	Code	Code Text	Code Version
https://www.phenxtoolkit.org	141201	fasting_c_peptide_assay

Key:

Fully-Specified Name

Value:

Component	Property	Time	System	Scale	Method
PhenX - fasting C-peptide assay for residual beta cell function protocol 141201	-	Pt	^Patient	-	PhenX

Key:

Basic Attributes

Value:

Class	Type	First Released	Last Updated	Change Reason	Panel Type
PANEL.PHENX	Clinical	Version 2.36	Version 2.66	Updated the PhenX ID from "PhenX." to "PX" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.	Panel