Assay human leukocyte antg (HLA) proto

General Details:

Name:: Assay human leukocyte antg (HLA) proto
Steward:: PhenX
Definition:: This protocol includes instructions for drawing, processing and storing blood according to the Type 1 Diabetes Genetics Consortium (T1DGC) Manual of Operations. Human Leukocyte Antigen is measured by using the linear array genotyping system method. The PhenX Infectious Diseases and Immunity Working Group would like to note that the science of HLA matching is rapidly advancing and evolving and multiple methods for HLA assays are available. To aid in comparability, the Infectious Diseases and Immunity Working Group recommends that the investigator record the make and manufacturer of equipment used and the repeatability and coefficients of variation for the assay. Please also note that the immobilized linear arrays used to genotype the samples were provided by Roche Molecular Systems and are not commercially available.
Registration Status:: Qualified

Designation:: PhenX - assay for human leukocyte antigen (HLA) genotyping protocol 160601
Tags:: Long Common Name

Definition:: This protocol includes instructions for drawing, processing and storing blood according to the Type 1 Diabetes Genetics Consortium (T1DGC) Manual of Operations. Human Leukocyte Antigen is measured by using the linear array genotyping system method. The PhenX Infectious Diseases and Immunity Working Group would like to note that the science of HLA matching is rapidly advancing and evolving and multiple methods for HLA assays are available. To aid in comparability, the Infectious Diseases and Immunity Working Group recommends that the investigator record the make and manufacturer of equipment used and the repeatability and coefficients of variation for the assay. Please also note that the immobilized linear arrays used to genotype the samples were provided by Roche Molecular Systems and are not commercially available.
Tags:: Source: Regenstrief LOINC

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Language Code:: en-US
Document:: NIH. NIDDK. Type 1 Diabetes Genetics Consortium Manual Of Operations. Blood Collection and Processing.

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Language Code:: en-US
Document:: Silke Rosinger, Sarah Nutland, Eric Mickelson, Michael D Varney, Bernard O Boehm, Gary J Olsem, John A Hansen, Ian Nicholson, Joan E Hilner, Letitia H Perdue, June J Pierce, Beena Akolkar, Concepcion Nierras, Michael W Steffes and T1DGC. Collection and processing of whole blood for transformation of peripheral blood mononuclear cells and extraction of DNA: the Type 1 Diabetes Genetics Consortium. Clinical Trials. 2010; 7: S65-S74.

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Language Code:: en-US
Document:: Josyf C Mychaleckyj, Janelle A Noble, Priscilla V Moonsamy, Joyce A Carlson, Michael D Varner, Jeff Post, Wolfgang Helmberg, June J Pierce, Persia Bonella, Anna Lisa Fear, Eva Lavant, Anthony Louey, Sean Boyle, Julie A Lane, Paul Sali, Samuel Kim, Rebecca Rappner, Dustin T Williams, Letitia H Perdue, David M Reboussin, Brian D Tait, Beena Akolkar, Joan E Hilner, Michael W Steffes, Henry A Erlich and T1DGC. HLA genotyping in the international Type 1 Diabetes Genetics Consortium. Clinical Trials. 2010; 7: S75-S87.

Key:

Related Names

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Ag	Assay human leukocyte antg (HLA) proto	Human Leukocyte Antigen
Leuc	Leuk	Leukocytes
Lkcs	Pan	Panel
PANEL.PHENX	Panl	Pnl
Point in time	Random	WBC
WBCs	White blood cell	White blood cells

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Related Codes

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Code System	Code	Code Text	Code Version
https://www.phenxtoolkit.org	160601	assay_for_human_leukocyte_antigen_(hla)_genotyping

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Fully-Specified Name

Value:

Component	Property	Time	System	Scale	Method
PhenX - assay for human leukocyte antigen (HLA) genotyping protocol 160601	-	Pt	^Patient	-	PhenX

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Basic Attributes

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Class	Type	First Released	Last Updated	Change Reason	Panel Type
PANEL.PHENX	Clinical	Version 2.36	Version 2.67	Updated the PhenX ID from "PhenX." to "PX" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.	Panel