Large artery atherosclerosis |
Large artery atherosclerosis |
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Either occlusive, or stenotic (greater than or equal to 50% diameter reduction or <50% diameter reduction with plaque ulceration or thrombosis or plaque with <50% diameter reduction that is seated at the site of the origin of the penetrating artery supplying the region of an acute lacunar infarct) vascular disease judged to be due to atherosclerosis in the clinically-relevant extracranial or intracranial arteries |
Cardio-aortic embolism |
Cardio-aortic embolism |
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Cardiac sources of embolism are segregated into high- and low-risk categories with reference to an objective 2% primary stroke risk threshold |
Small artery occlusion |
Small artery occlusion |
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Imaging evidence of a single and clinically relevant acute infarction less than 20 mm in greatest diameter within the territory of basal or brainstem penetrating arteries in the absence of any focal pathology in the parent artery at the site of the origin of the penetrating artery (focal atheroma, parent vessel dissection, vasculitis, vasospasm, etc.) |
Other uncommon causes |
Other uncommon causes |
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Specific disease processes not included in the first 3 categories that involve clinically-appropriate brain arteries, including, a. Unknown-cryptogenic embolism: Angiographic evidence of abrupt cut-off in an otherwise normal looking artery or subsequent complete recanalization of a previously occluded artery, b. Unknown: Other cryptogenic strokes that do not fulfill the criteria for cryptogenic embolism, c. Unclassified: Multiple competing etiologies, d. Incomplete evaluation: Failure to investigate for a relevant etiology in the absence of positive evidence |
Undetermined causes |
Undetermined causes |
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Undetermined causes |