NIH Common Data Elements (CDE) Repository

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Name:: Childhood AIS standardized classification and diagnostic evaluation (CASCADE) - primary chronic sub type
Steward:: NINDS
Definition:: Childhood AIS standardized classification and diagnostic evaluation (CASCADE) primary classification: chronic - patients with an initial vascular diagnosis (at 0-1 month) for "Primary Classification: Acute" are given a follow-up diagnosis based on studies obtained at or after 3-6 months that will capture any progression, stability or regression of the arteriopathy.
Registration Status:: Qualified

Value	Code Name	Code Description
Progressive Arteriopathy	Progressive Arteriopathy	Using the same radiographic techniques for comparison at 3-6 months or more beyond initial image: progression of arteriopathy or new arteriopathy.
Stable Arteriopathy	Stable Arteriopathy	Using the same radiographic techniques for comparison at 3-6 months or more beyond initial image: (1) no evidence of new or progressive arteriopathy and (2) no evidence of improvement in arteriopathy.
Reversible Arteriopathy	Reversible Arteriopathy	Using the same radiographic techniques for comparison at 3-6 months or more beyond initial image: easily recognized improvement/ resolution of arteriopathy without evidence of new arteriopathy.
Indeterminate Arteriopathy	Indeterminate Arteriopathy	Incomplete Follow-up

Designation:: Childhood AIS standardized classification and diagnostic evaluation (CASCADE) - primary chronic sub type
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Definition:: Childhood AIS standardized classification and diagnostic evaluation (CASCADE) primary classification: chronic - patients with an initial vascular diagnosis (at 0-1 month) for "Primary Classification: Acute" are given a follow-up diagnosis based on studies obtained at or after 3-6 months that will capture any progression, stability or regression of the arteriopathy.
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Document:: Bernard TJ, Beslow LA, Manco-Johnson MJ, Armstrong-Wells J, Boada R, Weitzenkamp D, Hollatz A, Poisson S, Amlie-Lefond C, Lo W, deVeber G, Goldenberg NA, Dowling MM, Roach ES, Fullerton HJ, Benseler SM, Jordan LC, Kirton A, Ichord RN. Inter-Rater Reliability of the CASCADE Criteria: Challenges in Classifying Arteriopathies. Stroke. 2016;47(10):2443-2449.<br /><br />Bernard TJ, Manco-Johnson MJ, Lo W, MacKay MT, Ganesan V, DeVeber G, Goldenberg NA, Armstrong-Wells J, Dowling MM, Roach ES, Tripputi M, Fullerton HJ, Furie KL, Benseler SM, Jordan LC, Kirton A, Ichord R. Towards a consensus-based classification of childhood arterial ischemic stroke. Stroke. 2012;43(2):371-377.