Nursed flat (180°) for CPP management |
Nursed flat (180°) for CPP management |
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Nursed flat (180°) for CPP management |
Sedation (low dose as required for mechanical ventilation) |
Sedation (low dose as required for mechanical ventilation) |
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Sedation (low dose as required for mechanical ventilation) |
Higher dose sedation for ICP control (not aiming for burst suppression) |
Higher dose sedation for ICP control (not aiming for burst suppression) |
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Higher dose sedation for ICP control (not aiming for burst suppression) |
Metabolic suppression for ICP control with high dose barbiturates or propofol |
Metabolic suppression for ICP control with high dose barbiturates or propofol |
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Metabolic suppression for ICP control with high dose barbiturates or propofol |
Neuromuscular blockade (paralysis) |
Neuromuscular blockade (paralysis) |
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Neuromuscular blockade (paralysis) |
CSF drainage <120 ml/day (<5 ml/hour) |
CSF drainage <120 ml/day (<5 ml/hour) |
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CSF drainage <120 ml/day (<5 ml/hour) |
CSF drainage greater than or equal to 120 ml (greater than or equal to 5 ml/hour) |
CSF drainage greater than or equal to 120 ml (greater than or equal to 5 ml/hour) |
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CSF drainage greater than or equal to 120 ml (greater than or equal to 5 ml/hour) |
Fluid loading for maintenance of cerebral perfusion |
Fluid loading for maintenance of cerebral perfusion |
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Fluid loading for maintenance of cerebral perfusion |
Vasopressor therapy required for management of cerebral perfusion |
Vasopressor therapy required for management of cerebral perfusion |
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Vasopressor therapy required for management of cerebral perfusion |
Mild hypocapnia for ICP control [PaCO2 4.6 – 5.3 kPa (35 - 40 mmHg)] |
Mild hypocapnia for ICP control [PaCO2 4.6 – 5.3 kPa (35 - 40 mmHg)] |
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Mild hypocapnia for ICP control [PaCO2 4.6 – 5.3 kPa (35 - 40 mmHg)] |
Moderate hypocapnia for ICP control [PaCO2 greater than or equal to 4 kPa (30 mmHg)] |
Moderate hypocapnia for ICP control [PaCO2 greater than or equal to 4 kPa (30 mmHg)] |
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Moderate hypocapnia for ICP control [PaCO2 greater than or equal to 4 kPa (30 mmHg)] |
Intensive hypocapnia for ICP control [PaCO2 <4 kPa (30 mmHg)] |
Intensive hypocapnia for ICP control [PaCO2 <4 kPa (30 mmHg)] |
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Intensive hypocapnia for ICP control [PaCO2 <4 kPa (30 mmHg)] |
Hyperosmolar therapy with mannitol up to 2 g/kg/24 hours |
Hyperosmolar therapy with mannitol up to 2 g/kg/24 hours |
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Hyperosmolar therapy with mannitol up to 2 g/kg/24 hours |
Hyperosmolar therapy with hypertonic saline up to 0.3 g/kg/24 hours |
Hyperosmolar therapy with hypertonic saline up to 0.3 g/kg/24 hours |
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Hyperosmolar therapy with hypertonic saline up to 0.3 g/kg/24 hours |
Hyperosmolar therapy with mannitol >2 g/kg/24 hours |
Hyperosmolar therapy with mannitol >2 g/kg/24 hours |
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Hyperosmolar therapy with mannitol >2 g/kg/24 hours |
Hyperosmolar therapy with hypertonic saline >0.3 g/kg/24 hours |
Hyperosmolar therapy with hypertonic saline >0.3 g/kg/24 hours |
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Hyperosmolar therapy with hypertonic saline >0.3 g/kg/24 hours |
Treatment of fever (temp.>38°C) or spontaneous temp. below 34.5°C |
Treatment of fever (temp.>38°C) or spontaneous temp. below 34.5°C |
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Treatment of fever (temp.>38°C) or spontaneous temp. below 34.5°C |
Mild hypothermia for ICP control with a lower limit of 35°C |
Mild hypothermia for ICP control with a lower limit of 35°C |
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Mild hypothermia for ICP control with a lower limit of 35°C |
Hypothermia below 35°C |
Hypothermia below 35°C |
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Hypothermia below 35°C |
Intracranial operation for progressive mass lesion, not scheduled on admission |
Intracranial operation for progressive mass lesion, not scheduled on admission |
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Intracranial operation for progressive mass lesion, not scheduled on admission |
Decompressive craniectomy |
Decompressive craniectomy |
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Decompressive craniectomy |
Head elevation for ICP control |
Head elevation for ICP control |
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Head elevation for ICP control |