Presence of encephalopathy (behavioral change or alteration in consciousness) |
Presence of encephalopathy (behavioral change or alteration in consciousness) |
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Presence of encephalopathy (behavioral change or alteration in consciousness) |
Improvement by clinical exam, MRI or both after acute event |
Improvement by clinical exam, MRI or both after acute event |
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Improvement by clinical exam, MRI or both after acute event |
Multifocal lesions predominantly involving white matter |
Multifocal lesions predominantly involving white matter |
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Multifocal lesions predominantly involving white matter |
New event of ADEM, 3 or more months with recurrence of the initial symptoms and signs (recurrent ADEM) |
New event of ADEM, 3 or more months with recurrence of the initial symptoms and signs (recurrent ADEM) |
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New event of ADEM, 3 or more months with recurrence of the initial symptoms and signs (recurrent ADEM) |
ADEM followed by a new clinical event also meeting criteria for ADEM, but involving anatomic areas of the CNS |
ADEM followed by a new clinical event also meeting criteria for ADEM, but involving anatomic areas of the CNS |
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ADEM followed by a new clinical event also meeting criteria for ADEM, but involving anatomic areas of the CNS |